OVERVIEW:
| Monoclonal UCHL1 antibody, Anti-UCHL1 antibody, UCHL1 antibody, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) antibody, BOS_6576 antibody, C88048 antibody, gad antibody, gracile axonal dystrophy antibody, neuron cytoplasmic protein 9.5 antibody, PARK5 antibody, PGP95 antibody, PGP 9.5 antibody, PGP9.5 antibody, protein gene product 9.5 antibody, R75593 antibody, ubiquitin carboxyl-terminal esterase L1 antibody, ubiquitin carboxyl-terminal hydrolase isozyme L1 antibody, ubiquitin carboxyl-terminal hydrolase L1 antibody, ubiquitin carboxy-terminal hydrolase L1 antibody, ubiquitin C-terminal hydrolase antibody, ubiquitin C-terminal hydrolase-L1 antibody, ubiquitin thioesterase L1 antibody, ubiquitin thiolesterase L1 antibody, UCH-L1 antibody |
| Human, Mouse, Rat |
| ELISA, WB |
| UCHL1 antibody was raised in Mouse using a recombinant human protein purified from E.coli (GST-UCHL1) as the immunogen |
SPECIFICATIONS:
| Mouse |
| AF3F8 |
| IgG1 kappa |
| UCHL1 antibody was purified by ammonium sulfate precipitation |
| Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
STORAGE & SAFETY:
| Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
Usage Assay Information:
| WB: 1:500-2000 |
GENERAL INFORMATION:
| Ubiquitin carboxy-terminal h d l L1 hydrolase (UCHL1) is a deubiqutinating enzyme. Ubiquitin UCHL1, also known as PGP9.5, is a protein of 223 amino acids and one of the most abundant proteins in the brain (1-2% of the total soluble protein). Although it was originally characterized as a deubiquitinating enzyme recent studies indicate that it also functions as a ubiquitin (Ub) ligase and a mono-Ub stabilizer. A large amount of mono-Ub is tightly associated with UCHL1, inhibiting the degradation of mono-Ub in the brain. |
